FoldUnfold: Prediction of disordered regions in protein chain

Scale
Averaging frame
Reliable frame Reliable frame is usually equal to averaging frame
Threshold
analyse regions also in those proteins which are predicted as fully disordered (average value for the whole protein is below threshold)
write profile

A protein is predicted as being disordered throughout its length if the average value of the parameter over the protein is less than threshold. If the average value of the parameter over a protein is higher than threshold, the protein is searched for disordered regions.

A region is predicted as being disordered if the average value of the parameter over this region is less than threshold and the region is greater or equal in size to the reliable frame.

Target sequence in FASTA format

Report any bug in the prediction service please send to author of electronic design M.Yu.Lobanov

Please cite the prediction server:
  • Oxana V. Galzitskaya, Sergiy O. Garbuzynskiy, Michail Yu. Lobanov.
    FoldUnfold: web server for the prediction of disordered regions in protein chain.
    Bioinformatics, 2006, 22 (23), 2948-2949. pdf
  • Oxana V. Galzitskaya, Sergiy O. Garbuzynskiy, Michail Yu. Lobanov.
    Prediction of natively unfolded regions in protein chains.
    Molecular Biology (Moscow), 2006, 40 (2), 341-348. Abstract
  • Oxana V. Galzitskaya, Sergiy O. Garbuzynskiy, Michail Yu. Lobanov.
    Prediction of amyloidogenic and disordered regions in protein chains.
    PLoS Computational Biology, 2006, 2 (12), e177. pdf
  • Sergiy O. Garbuzynskiy, Michail Yu. Lobanov, Oxana V. Galzitskaya.
    To be folded or to be unfolded?
    Protein Science, 2004, 13 (11), 2871-2877. pdf